Symptoms can be mild or serious and can include: If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. The primary symptom of OI is lightheadedness or fainting. This can cause Zetia to be less effective. However, its important that you dont stop taking Zetia without first talking with your doctor. Zetia is approved to treat certain forms of high cholesterol in adults when used with a low-cholesterol diet. Its not known if Zetia is safe to take during pregnancy. Weight gain isnt a side effect reported in clinical studies of Zetia. Zetia is approved to treat different types of high cholesterol. Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. It can be taken with or without fenofibrate in adults. These symptoms can be signs of an infection. In people with POTS, more blood collects in the lower body when standing upright. Sometimes doctors will recommend taking both a statin medication and Zetia for high cholesterol. Lipitor is part of the statin drug class. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. 22% in people who used Zetia with fenofibrate, 20% in people who used Zetia with fenofibrate, people who used Zetia with atorvastatin or simvastatin had their LDL levels reduced by an average of 21% to 27% (the percentage varied depending on the dosage used), people who used atorvastatin or simvastatin alone had their LDL levels reduced by an average of 7%, people who used Zetia had their sitosterol levels decreased by an average of 21% and their campstrol levels decreased by an average of 24%, people who used a placebo had their sitosterol levels decreased by an average of 4% and their campstrol levels decreased by an average of 3%, bile acid sequestrants, such as cholestyramine (Prevalite, Questran), colesevelam (Welchol), and colestipol (Colestid), statins, such as atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor), Both Zetia and Lipitor are FDA-approved to treat the following conditions* in adults when used with a. Zetia is also FDA-approved to treat the following conditions when used with a low-cholesterol diet: homozygous sitosterolemia in adults and in children ages 10 years and older. Zetia is contraindicated under the following conditions: Zetia tablets should be stored at a room temperature of 77F (25C) in a tightly sealed container away from light. For more information about how the drug is used, see the Zetia uses section below. Sharing this information can help you avoid potential interactions. If your cholesterol levels havent started to improve, they may recommend a different treatment for you. A large review by the American Heart Association compared studies of CoQ10. This lack of blood to the brain and other organs can cause a variety of symptoms, including: Fainting. Youll likely take it once a day. If you would like to report to the FDA a side effect youve had with Zetia, you can do so through MedWatch. You can use the study as a second opinion to make health care decisions. Zetia (ezetimibe) is prescribed to lower high cholesterol in adults and some children, along with a low cholesterol diet. POTS-related fatigue is physical in nature . Dizziness is a rare side effect of taking Zetia. However, if the side effects last longer than . voice changes. sinusitis. Zetia has a well-documented safety profile. When this happens, more cholesterol can then be cleared from your blood by your liver. Like most drugs, Zetia can cause an allergic reaction in some people. These conditions can raise your risk of muscle problems while taking Zetia. Learn more about how grapefruit may interact with medications. A life-changing condition called POTS, which can cause fainting, irregular heartbeats and dizziness, particularly among young women, appears to be on the rise as a result of the coronavirus pandemic. We avoid using tertiary references. However, excessive alcohol use can damage your liver over time. Increased liver enzymes can be a sign of liver damage. Zetia is meant to be used as a long-term treatment. Examples of other drugs that may be used to treat primary high cholesterol include: Examples of other drugs that may be used to treat mixed high cholesterol include: Examples of other drugs that may be used to treat homozygous familial hypercholesterolemia include: Examples of other drugs that may be used to treat homozygous sitosterolemia include: You may wonder how Zetia compares with other medications that are prescribed for similar uses. They may suggest foods that can help lower your cholesterol and reduce your risk of weight gain. Hot and cold spells. Drugs in this class prevent your small intestine from absorbing cholesterol. (A drug class is a group of medications that work in a similar way.) If your doctor has prescribed Zetia and youre interested in using ezetimibe instead, talk with your doctor. Have your doctor measure your heart rate sitting and standing. Its not clear if CoQ10 prevents muscle-related side effects when Zetia is taken with a statin, but it might help. They can both be taken with or without food. Ways to reduce the symptoms. (A class of drugs is a group of medications that work in a similar way.) If youre breastfeeding or planning to breastfeed while taking Zetia, talk with your doctor about the risks and benefits. Zetia shouldnt cause weight gain or weight loss. Zetia can cause certain side effects, some of which are more common than others. As with all medications, the cost of Zetia can vary. If youre concerned about joint pain while using Zetia, talk with your doctor. Zetia contains the active drug ezetimibe. Symptoms of atherosclerosis may include confusion, fatigue (lack of energy), trouble breathing, or pain in your chest, arms, or legs. Total cholesterol levels were reduced by an average of: LDL (bad) cholesterol levels were reduced by an average of: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. Other drugs are available that can treat your conditions. 5.8k views Answered >2 years ago. If you need financial support to pay for Zetia, or if you need help understanding your insurance coverage, help is available. For treatment of mixed hyperlipidemia, Zetia is indicated to reduce total cholesterol, LDL cholesterol, non-HDL cholesterol, and ApoB. Also, Zetia use may cause increased liver enzyme levels, especially if its taken with a statin drug. unusual tiredness or weakness. Crestor is available in a generic form called rosuvastatin. Zetia contains the active drug ezetimibe. Statins are commonly prescribed with Zetia to treat certain types of high cholesterol. Sometimes brain zaps are also accompanied by dizziness, pain, or tinnitus, a ringing in the ears. For information on the effectiveness of Zetia, see the Zetia uses section below. You should also look for supplements from reputable manufacturers. Total cholesterol is the overall amount of cholesterol found in your blood. If youre pregnant or breastfeeding, or if youre planning to become pregnant or breastfeed, tell your doctor. Other interactions can increase side effects or make them more severe. If your muscle-related side effects dont go away or become severe, tell your doctor right away. It also helps keep the drug from harming the environment. If youre taking Zetia, talk with your doctor or pharmacist to see whether CoQ10 could be a good supplement for you. As patients we need to be constantly wary because it is increasingly clear that the pharmas have abrogated their responsibility on our behalf. In most cases, these side effects should be temporary. . And some may be easily managed, too. If you have high cholesterol with hypertension (high blood pressure) or diabetes, youll likely have to take other drugs with Zetia to treat these conditions. Treatment is targeted at relieving low blood volume or regulating circulatory problems that may cause the disorder. Leqvio is a prescription drug used to lower cholesterol. High cholesterol can raise your risk of heart disease. In order to diagnose POTS, your doctor will need to measure your heart rate when you are sitting at rest. (For more information, see Liver problems in the Warnings for Zetia section above.). Zetia is indicated as an adjunct to a low-cholesterol diet for treatment of the following types of hyperlipidemia: For treatment of primary hyperlipidemia, Zetia is indicated to reduce total cholesterol, low-density lipoprotein (LDL) cholesterol, non-high-density lipoprotein (non-HDL) cholesterol, and apiloprotein B (ApoB). Some people with POTS also may have one or more . Also tell them about any vitamins, herbs, and supplements you use. POTS was also linked, to a lesser degree, to Covid vaccination with an mRNA vaccine, according to the new study. When taken together, it should be administered at least 2 hours before or 4 hours after a bile acid sequestrant. For this purpose, Zetia may be used alone or with fenofibrate. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. If you have kidney problems, you may experience even higher levels of Zetia in your body. POTS is defined by its particular symptoms and an excessive increase in heart rate upon standing. If you have a history of heavy alcohol use and are taking Zetia with a statin drug, you may have a higher risk of side effects. If the side effects seem life threatening or if you think youre having a medical emergency, immediately call 911 or your local emergency number. Tell them about all prescription, over-the-counter, and other drugs you take. These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Crestor, or with both drugs (when taken individually). Zetia may be used with statin drugs to treat the following conditions in adults: Statins are another class of medications used to lower cholesterol. Examples of statin drugs include atorvastatin (Lipitor) and simvastatin (Zocor). The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The heart beats faster to pump it up to the brain, but with little success. Despite having lower total cholesterol than white people, African Americans are at greater risk of dying from heart disease. However, you shouldnt stop taking Zetia without first talking with your doctor. Clinical studies have shown Zetia to be effective for treating homozygous sitosterolemia when used alone. Do my other medications increase my risk of side effects with Zetia? Note: Zetia isnt approved to lower these types of cholesterol: Cholesterol is measured in several ways. Read More. But in studies, some people had to stop taking the drug due to feeling dizzy. At the end of the study, researchers found that: Mixed hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol and fats are cleared from your body. Learn about the drugs dosage, forms, strengths. Postural Orthostatic Tachycardia Syndrome (POTS) is a blood flow disorder that causes a sudden spike in heartbeat with no change in blood pressure when going from a horizontal or seated to a standing position. You may not have any symptoms of gallstones unless they cause your gallbladder to swell. Zetia and Lipitor have some similar side effects and others that vary. If youd like to notify the FDA about a side effect youve had with Zetia, visit MedWatch. Muscle problems were reported in clinical studies of adults and children who took Zetia with statin drugs. Clinical studies looked at Zetia for the treatment of primary hyperlipidemia in adults and in children ages 10 years and older. This helps prevent others, including children and pets, from taking the drug by accident. Each type is described below in more detail. Homozygous sitosterolemia is a genetic condition caused by a mutation (change) in the genes that control how plant sterols are cleared from your body. Covers lawsuits, malpractice, class actions, fraud, legislation, regulation, enforcement. For those who aren't familiar with POTS, it is an often-disabling neurological condition that causes your heart rate to rise a great deal when you are upright, and often blood pressure drops when you are upright (when it should be rising), and it causes fainting, fatigue, headache, nausea, face and hand tingling, and blood pooling in legs. For this purpose, Zetia is used with a low-cholesterol diet (but with no other drugs) in adults and in children ages 10 years and older. Medications in this class prevent your small intestine from absorbing cholesterol. Zetia and Crestor are both brand-name drugs. Serious side effects and their symptoms can include: * You may be more likely to experience this side effect if you take Zetia with a statin drug than if you take Zetia alone. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. This part of the nervous system controls functions that we don't actively control, such as heart rate, blood pressure, perspiration, and temperature. Ask your doctor what other medications are better options for you. pain in your arms or legs. Its not known how many adults and children experienced muscle pain in clinical studies of other conditions treated with Zetia and statin drugs. However, studies have found both Zetia and Lipitor to be effective for lowering cholesterol. Dr. John Szawaluk answered. And do not stop using Zetia unless your doctor recommends it. The side effects of Zetia in children are similar to the side effects in adults. Its intestinal molecular target is the Niemann-Pick C1-Like 1 (NPC1L1) sterol transporter. * This is a partial list of mild side effects from Zetia. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about . But the condition isn't well understood, and many patients are dismissed as having anxiety, delaying diagnosis. Zetia is approved to treat certain forms of high cholesterol in children ages 10 years and older when used with a low-cholesterol diet. Dont take an extra dose to make up for your missed dose. You should always consult your doctor or another healthcare professional before taking any medication. Your doctor may stop your Zetia treatment if it isnt safe or effective for you. Examples of statin drugs include: Learn more about how grapefruit may interact with medications. Talk with your doctor to learn more about which medications are right for you. Some people have mild symptoms, while for others it can have a big impact on their everyday lives. If you drink alcohol and have questions about drinking it during Zetia treatment, talk with your doctor. Zetia contains the active drug ezetimibe. But reviews and complaints about medications, including Zetia, may not be as reliable as other types of consumer reviews. The manufacturer of Zetia hasnt given birth control recommendations for males using the drug. Zetia (ezetimibe) is prescribed to lower high cholesterol in adults and some children, along with a low cholesterol diet. People with this condition have high levels of LDL (bad) cholesterol, high levels of triglycerides, and low levels of HDL (good) cholesterol. An allergic reaction is possible after using Zetia. Both drugs are typically taken once each day. Its also not known if the drug is safe to take while breastfeeding or whether the drug passes into breast milk. In studies, weight changes didnt occur in people who took the drug. Taking Zetia with a statin drug may increase your risk of developing some mild or serious side effects. Your child can take Zetia with or without food. 6. Many rare diseases have limited information. 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