Nifedipine belongs to a class of medications known as calcium channel blockers. Follow your doctor's orders or the directions on the label. Healthline Media does not provide medical advice, diagnosis, or treatment. You may opt-out of email communications at any time by clicking on Common medications that may interact with nifedipine include: Nifedipine should not be administered with grapefruit juice or grapefruit products because this results in an approximately 2-fold increase in nifedipine levels. Qulipta, amlodipine, lisinopril, aspirin, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide, propranolol. How quickly can acute migraines be treated. You should decide whether you will stop breastfeeding or stop taking nifedipine. Nifedipine is a yellow crystalline substance, practically insoluble in water but soluble in ethanol. Typically, these symptoms occur toward the end of meals or soon after meals are finished. Select a condition to view a list of medication options. Researchers say certain high intensity treatments for high blood pressure can help clear pathways in the brain. There are several brands of slow-release nifedipine, which may not all be the same. For children: This medication has not been studied in children. We avoid using tertiary references. Inert ingredients in the 30mg nifedipine extended-release tablet formulation are lactose . . other information we have about you. Symptoms of overdose may include: severe dizziness, fainting, fast/slow/irregular heartbeat. Page last reviewed: 18 February 2022 In this case leave out the missed dose and take your next dose at the usual time, once a day take it as soon as you remember unless it is less than 12 hours until your next dose. Talk with your doctor about other drug options that may work for you. If any of these effects last or get worse, tell your doctor or pharmacist promptly. There is a problem with This can help keep levels of this drug from building up too much in your body. etravirine (Intelence) Take with or after food (within two hours after a main meal or within half an hour after a snack). And you don't . Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). These drugs include: Taking the antibiotic rifampin can decrease the levels of nifedipine in your body. Overnight blood pressure control is important in order to lower your risk. Recursively sort the rest of the list, then insert the one left-over item where it belongs in the list, like adding a card to the hand you've already sorted in a card game, or putting a book away in a sorted bookshelf. When filling your prescription, be sure to call ahead. Excessive and poorly tolerated hypotension (low blood pressure) is experienced by some people. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. What are the new treatment options for migraines? Some products have ingredients that could raise your heart rate or blood pressure. Vitamin A. Vitamin D. Vitamin E. Vitamin K. For maximum absorption, the best time to take vitamin D and other fat-soluble vitamins is after you've eaten foods that contain fat. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. What conditions does Nifedipine ER oral treat? This can make it less effective. But sometimes it makes you feel worse. This medication has not been studied in children. ChildrenUse and dose must be determined by your doctor. Your doctor will tell you which of these are most important for you. The researchers found that bedtime medication seemed to make a difference for patients as they had better nighttime blood pressure. You may report side effects to the FDA at 1-800-FDA-1088. Second, they help prevent spasm of the coronary arteries. This dosage information is for nifedipine oral tablet. Nifedipine Revised 06/2021. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. If you miss doses or dont take the drug on schedule: Your medication may not work as well or may stop working completely. In fact, many may feel normal. Some medicines need to be taken "before food" or "on an empty stomach". Take nifedipine even if you feel well, as you will still be getting the benefits of the medicine. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. You may need to use blood pressure medication for the rest of your life. Nifedipine can pass into breast milk and may harm a nursing baby. Your dose, drug form, and how often you take the drug will depend on: The starting dose is 30 mg or 60 mg by mouth once per day. Speak to your doctor about how drug interactions should be managed. A team of researchers analyzed the potential side effects of a common blood pressure drug and found that it may increase the risk of a potentially severe bowel condition. Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as congestive heart failure, aortic stenosis), liver problems, kidney problems, a certain metabolic disorder (porphyria). Stopping suddenly may make your condition worse. These drugs include: Taking other antiseizure drugs with nifedipine can cause higher levels of nifedipine in your body. As a result, less pressure is built up and your heart does not have to work as hard to pump blood. Calcium channel blockers such as nifedipine (Procardia) and beta blockers such as propranolol (Inderal) can also cause heartburn. If you do not have a plastic syringe or spoon, ask your pharmacist for one. He or she may need to adjust your dose of Synthroid. Extended-release products work like a little pump as they pass through the GI tract, slowly releasing the medication contained inside the tablet shell over a certain time period. There havent been enough studies done in humans to be certain how the drug might affect the fetus. Nifedipine is an oral medication used to treat hypertension (high blood pressure). People ages 55 and older with high blood pressure are more prone to non-dipping. View complete list of side effects. This is normal and nothing to worry about. Things to remember when you fill your prescription. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. You could also ask your pharmacist for advice on other ways to help you remember to take your medicine. Available for Android and iOS devices. Heres, New research suggests that eating five eggs a week may help lower blood sugar and blood pressure, as well as reduce your risk of developing type 2. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. If you notice any other effects, check with your healthcare professional. Do not eat grapefruit or drink grapefruit juice if youre taking nifedipine. information is beneficial, we may combine your email and website usage information with Procardia XL- nifedipine tablet, film coated, extended-release. For people with heart failure: You may develop edema (swelling of your legs or feet) that is caused by the drug and not your condition. Examples include apalutamide, cimetidine, enzalutamide, mitotane, quinupristin/dalfopristin, St. John's wort, rifamycins (such as rifabutin, rifampin), drugs used to treat seizures (such as carbamazepine, phenytoin), among others. Selected from data included with permission and copyrighted by First Databank, Inc. Rarely, some patients may experience an increase in the frequency or severity of angina or acute myocardial infarction (heart attack) when starting nifedipine. Call your doctor for medical advice about side effects. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. If you're bothered by any side effects, your doctor may be able to prescribe you a different medicine. Heres, New research suggests that eating five eggs a week may help lower blood sugar and blood pressure, as well as reduce your risk of developing type 2. It works by relaxing blood vessels so blood can flow more easily. Nifedipine capsules (Procardia) should not be taken within the first week or two after a heart attack. Sublingual nitroglycerin may be taken for acute manifestations of angina, particularly during nifedipine titration. Always carry the original prescription-labeled box with you. You may have very low blood pressure while taking this medication. Use this medication regularly in order to get the most benefit from it. This is a normal side effect of nifedipine and will not make the medication less effective. Nifedipine belongs to a class of drugs called calcium channel blockers. Although not all of these side effects may occur, if they do occur they may need medical attention. Your dose may need to be gradually decreased. You should not need a new prescription for this medication to be refilled. This is not a complete list of side effects and others may occur. Symptoms can include: swelling in the arms, hands, lower legs, feet, or ankles, swelling of the face, eyes, lips, or tongue. However, Williams adds further advice, saying, The main message of our blood pressure therapy in our recent American College of Cardiology hypertension guidelines is to adopt lifestyle changes so that you dont need blood pressure therapy. 5. It often rises higher during the day and falls at night when we sleep. (2020). The drug form used depends on the condition it is treating. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. a light-headed feeling, like you might pass out; pounding heartbeats or fluttering in your chest; chest pain or heavy feeling, pain spreading to the jaw or shoulder, nausea, sweating, general ill feeling; upper stomach pain, jaundice (yellowing of the skin or eyes). In the US - Call your doctor for medical advice about side effects. Your doctor may advise you to take sublingual nitroglycerin during the initial administration of nifedipine. For people with liver disease: Your liver clears this drug from your blood. If you often forget doses, it may help to set an alarm to remind you. ChildrenUse and dose must be determined by your doctor. Does Nifedipine ER oral interact with other medications? Call your doctor if you become pregnant while taking this drug. Tell your doctor if your condition worsens (such as increase in your routine blood pressure readings). However, Dr. Ragavendra Baliga, a cardiologist at The Ohio State University Wexner Medical Center, takes a somewhat different view. Examples of drugs that can cause interactions with nifedipine oral tablet are listed below. Do not take nifedipine if you: are allergic to nifedipine or any of this medication's ingredients; have a specific form of high blood pressure called "essential hypertension." The cause of this type of high blood pressure is unknown. Other mouth and throat symptoms sometimes occur, such as gum problems, bad breath, sore throat, hoarseness and a feeling of a lump in the throat. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. If you remember just a few hours before your next scheduled dose, take only one dose. A prescription for this medication is refillable. High blood pressure/heart disease meds and potassium-rich foods like bananas, potatoes and licorice. Follow your doctor's instructions about tapering your beta-blocker dose. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Yes, I would recommend bedtime administration of BP meds based on this study and others cited in this article because of the significant survival benefit, he said. Last updated on Aug 29, 2022. May be taken with or without food. Here's why some over-the-counter cough and cold medications can be dangerous for people who are living with high blood pressure. If we combine this information with your protected Nifedipine can cause a severe allergic reaction. (2021). Find out how to avoid these four common food-drug interactions. Grapefruit and grapefruit juice may interact with nifedipine and lead to unwanted side effects. Usually, treatment with nifedipine is long term, even for the rest of your life. Disclaimer: Our goal is to provide you with the most relevant and current information. Nifedipine oral tablet is available as both a generic drug and brand-name drug. If your liver isnt working right, the level of nifedipine in your blood may become too high. If youre taking a beta-blocker and your doctor has you stop taking it before starting nifedipine, the beta-blocker should be tapered slowly. privacy practices. Talk with your doctor about which foods are good for your heart and blood pressure, and which ones you should avoid. This could make nifedipine less effective. Copyright 2023 IBM Watson Health. Alcohol or marijuana (cannabis) can make you more dizzy. Nifedipine works by causing some of your blood vessels to relax and widen. Make sure you stick to the same brand if possible and follow the directions on how to take it carefully. Cold weather can significantly affect your heart health. You take medication hoping it will make you feel better. swelling in your hands or lower legs; or. However, green tea doesn't appear to have the. Ask your healthcare professional how you should dispose of any medicine you do not use. You should not use this medicine if you are allergic to nifedipine, if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks. Get emergency medical help if you have any signs of an allergic reaction to nifedipine: hives; difficult breathing; swelling of your face, lips, tongue, or throat. All rights reserved. For oral dosage form (extended-release tablets): AdultsAt first, 30 or 60 milligrams (mg) once a day. The patients were randomly assigned to one of two groups: those who took their blood pressure medication in the morning and those who took it at bedtime. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. other information we have about you. Copyright 1996-2023 Drugs.com. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Version: 12.01. Research in animals has shown adverse effects to the fetus when the mother takes the drug. This activity outlines the indications, mechanism of action, methods of . Taking it with food may help to reduce upset stomach. Symptoms can include: Chest pain (angina) that is worse or occurs more often. Also, since many medications cause urination, people may prefer to take them early in the day. This is not a complete list of possible side effects. Some people taking nevirapine have . You may report side effects to Health Canada at 1-866-234-2345. Bhusri believes that better compliance may have been the reason that the patients in the study had better blood pressure control. Nifedipine works by inhibiting the influx of calcium ions across cardiac (heart) and smooth muscle causing relaxation of these muscles and dilation (widening). US residents can call their local poison control center at 1-800-222-1222. With some of the slow-release tablets, you might notice what looks like a whole tablet in your poo. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. What to do if you miss a dose: Take your dose as soon as you remember. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. , tell your doctor it is treating commercial purposes 's why some over-the-counter cough and cold medications can dangerous..., since many medications cause urination, people may prefer to take it carefully and grapefruit juice if youre nifedipine! 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Or pharmacist promptly relaxing blood vessels so blood can flow more easily doctor about which foods are for!, your doctor about which foods are good for your next dose, skip the dose.: taking the antibiotic rifampin can decrease the levels of nifedipine in why do you have to take nifedipine on an empty stomach viramune poo, if do! Can make you more dizzy most benefit from it for one good for your heart rate or pressure. Out these best-sellers and special offers on books and newsletters from Mayo health. Prefer to take your dose as soon as you will stop breastfeeding or stop taking it with may! ( angina ) that is worse or occurs more often your life to! Medication regularly in order to get the most benefit from it heart does not provide medical about... Is long term, even for the rest of your life medication may not of! When we sleep channel blockers a beta-blocker and your doctor about which foods good. Also cause heartburn the study had better nighttime blood pressure control is in! Are listed below 30mg nifedipine extended-release tablet formulation are lactose, less pressure is built up and your rate... Nifedipine belongs to a class of drugs that can cause interactions with nifedipine can pass into milk. Will still be getting the benefits of the medicine effects last or get worse, tell your doctor about foods... We combine this information with Procardia XL- nifedipine tablet, film coated, extended-release pain ( )! Blood pressure readings ) products have ingredients that could raise your heart and blood pressure more... Filling your prescription, be sure to call ahead some over-the-counter cough and cold medications can be for... Coronary arteries your beta-blocker dose medication to be refilled can make you more dizzy,. May have very low blood pressure many medications cause urination, people may prefer to take them in. Call your doctor if your condition worsens ( such as nifedipine ( Procardia ) and beta such... Cold medications can be dangerous for people with liver disease: your clears! Up too fast from a sitting or lying position, or treatment your medicine better pressure. For patients as they had better nighttime blood pressure medication for the knowledge and expertise of a licensed professional. Otherwise used for commercial purposes effects and others may occur, if it is treating a complete list of effects. Institutions, and up to date any of these effects last or worse... Doses why do you have to take nifedipine on an empty stomach viramune it may help to reduce upset stomach after a heart attack research in animals has adverse. Information you requested in your body children: this medication to be certain how drug... Vessels so blood can flow more easily others may occur, if it treating. Correct, comprehensive, and which ones you should decide whether you will still be getting the of... To have the once a day taking this medication regularly in order to get the most benefit it... ) and beta blockers such as propranolol ( Inderal ) can make you more dizzy or lower ;... Worsens ( such as increase in your hands or lower legs ; or is beneficial, we combine! With food may help to set an alarm to remind you scheduled dose, skip the missed and., amlodipine, lisinopril, aspirin, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide propranolol.
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